Wednesday, August 4, 2010

Army’s Vaccine Plan: Inject Troops With Gas-Propelled, Electro-Charged DNA

The Army’s got a one-two punch to perfect vaccinations and offer scientists the ability to quickly develop inoculations that stave off new dangers. First, they’ll shoot troops up using a “gene gun,” that’s filled with DNA-based vaccines. Then they’ll follow it up with “short electrical pulses to the delivery site.”

The Pentagon’s still after a comprehensive way to inoculate troops and civilians against existing illnesses, rapidly respond to emerging threats, and even predict pathogenic mutations before they happen. To that end, the military’s already funding a handful of projects, from plant-based vaccine production to genetic signatures for ultra-early diagnosis.

In a small business solicitation released last week, the Army put out a call for “Multiagent Synthetic DNA Vaccines Delivered by Noninvasive Electroporation.” The program would start by transforming conventional development methods, like standard egg-based vaccines.

The old-school methods are slow, don’t allow for readily combined vaccines, and can pose sterility risks. DNA-based vaccines, on the other hand, would be quick to engineer and offer reliable immunity — provided the DNA can enter host cells to trigger the production of immunity proteins...

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